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| There are a few medications that are currently in the works to fight obesity. Some of these are completely new chemical formulas while others are a mixture of existing medications on the market. These are being created to help with the ever increasing weight problems that many developed nations are facing. It is still undetermined at the time of this writing if any of these will ever make it to the market as they still must pass stringent testing to ensure quality performance and safety. One of the newly created medications is named Lorcaserin. This product has a similar chemical structure to Fenfluramine but unlike Fenfluramine, it has not shown any of the negative heart related problems caused by its use. Another positive going for Lorcaserin is that studies have shown that there is a very low chance of it being abused. Testing has shown that there is not much of a chance that someone would take it to get an elevated sense of well being or any other factor that would make it addictive. This is a definite positive for it when it comes under analysis by the FDA. Another prescription diet pill in the making is Contrave, It has shown better weight loss factors than Lorcaserin but perhaps its side effects could be a little greater. Contrave is actually a combination medication consisting of Naltrexone and bupropion. Both are already in pharmacies and are being used for drug addictions and smoking addiction or depression respectively. But studies are proving that when they are mixed in a special blend that the resulting mixture is producing some great weight loss results. Qnexa is another mixture medication being studied for obesity. Its results are showing to be strong and this mixture could result in one of the better formulas if approved by the FDA. Qnexa is a mixture of the existing drug Phentermine (already being prescribed for weight loss) and Topamax, which is prescribed mainly for treating epilepsy. Once again, when these two are mixed together in the right amounts they are producing significant weight loss in patients. Some believe this may have the best potential compared to the previous two in this article but the FDA would still need to determine if its rewards to risks ratio is good enough to be approved. All three previous medications here have gone through their stage three testing and have been submitted to the FDA, it is expected that we could hear back from the FDA sometime this fall about each one, or shortly after. There are however still some other worthy opponents in the search for the ultimate diet pill. These however are a little further behind in their research and development but could still hold a lot of potential. These are the trial medications of Tesofensine and Empatic. In recent tests, Tesofensine has shown to be perhaps twice as effective as current anti-obesity medication Sibutramine. If stage three testing results still support this evidence from earlier testing, and the side effects are within reason, this could be the biggest of all prescription diet pills. However, this substance still needs to have the more exhaustive stage three testing performed where much more information will be discovered on its effectiveness and overall side effects. Stage three testing will take about a year once they have commenced and then would have to be submitted to the FDA then if all goes well you may hear back from the FDA 10 months later. As a result, it will still be most likely at least two years away before we hear if Tesofensine will ever make it to pharmacies or not. Last but not least is the trial medication called Empatic. Empatic is actually another mixture drug from the same makers of Contrave. This combination consists of Zonisamide and Bupropion. Zonisamide is an anti-convulsant and Bupropion is as already mentioned, is an anti-depressant or an aid used to stop smoking. It too needs further testing with phase three tests. But so far so good, it too like the others has shown to be effective enough that it has exceeded the FDA’s requirements for a medication to be considered for obesity. This one like Tesofensine could take at least another two years before even hearing back from the FDA about its acceptance or not, that is, if it ever is even submitted to them. | |
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, Sep 15 2010, 12:58 PM EDT
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